Were a sufficiently devastating full-scale nuclear war to break out, the organizational and perhaps even demographic prerequisites for these technologies would be irrevocably undermined, for decades at least. And the resulting chaos, famine, and destruction that would follow may well prevent the return of a truly large, truly centralized administrative state in a globalized economy for even longer. But as to whether this would be merely a road bump in human history or a decisive turning point in it is harder to say.